2-(4-heptylphenethyl)-6-hydroxybenzoic acid - Names and Identifiers
2-(4-heptylphenethyl)-6-hydroxybenzoic acid - Physico-chemical Properties
Molecular Formula | C22H28O3
|
Molar Mass | 340.46 |
Density | 1.100±0.06 g/cm3(Predicted) |
Boling Point | 477.8±33.0 °C(Predicted) |
Solubility | 10 mM in DMSO |
pKa | 3.06±0.30(Predicted) |
Storage Condition | -20℃ |
In vitro study | MG149 targets the acetyl-coenzyme A binding site and inhibits acetyltransferase activity in nuclei extracted from tissue samples from different brain regions of mice. MG149 also inhibits p53 and NF-κB signaling pathways. |
2-(4-heptylphenethyl)-6-hydroxybenzoic acid - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 2.937 ml | 14.686 ml | 29.372 ml |
5 mM | 0.587 ml | 2.937 ml | 5.874 ml |
10 mM | 0.294 ml | 1.469 ml | 2.937 ml |
5 mM | 0.059 ml | 0.294 ml | 0.587 ml |
Last Update:2024-01-02 23:10:35
2-(4-heptylphenethyl)-6-hydroxybenzoic acid - Reference Information
biological activity | MG149 is a potent histone acetyltransferase inhibitor, its IC50 for Tip60 and MOF were 74 μm and 47 μm, respectively. MG149 (Tip60 HAT inhibitor) is a potent histone acetyl transfer inhibitor with IC50 of 74 μm and 47 μm for Tip60 and MOF, respectively. |
Target | Value |
MOF
(Cell-free assay)
| 47 μM |
Tip60
(Cell-free assay)
| 74 μM |
Last Update:2024-04-09 19:05:17